Getting out of our own way.
There may be other obstacles between you and your goals, the life you want to live. But the greatest obstacle is us, ourselves. The fear, attachment, emotion associated with doing the work that can make our lives better.
The key is to work as a professional, doing things because they need to be done, without worrying about whether they will lead to the desired outcome or not.
There is a time to be a CEO and there is a time to be the worker. The problem arises when the worker in us starts acting like the CEO.